DeepNiche

CRISPR in the clinic

VERVE-102 base edit cuts PCSK9 in first-in-human trial

One intravenous infusion of VERVE-102 produced dose-dependent mean PCSK9 reductions of 51% to 88% and LDL-cholesterol reductions of 9% to 62% in 35 adults.

source: pubmed.ncbi.nlm.nih.gov

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